Assist.Prof.Dr. Wikunda Limpiangkanan,MD.
“Thai dermatologist who was granted research scholarship in field of laser surgery from Harvard University in 2011-2013 and has filed for 6 U.S.patents which could be useful in treating some skin conditions in the near future”
ผู้ช่วยศาสตราจารย์แพทย์หญิง วิกันดา ลิมปิอังคนันต์ (Wikunda Limpiangkanan) แพทย์เฉพาะทางผิวหนัง (วว.ตจวิทยา) หมอผิวหนังคนไทยที่ได้รับทุนวิจัยด้านศัลยศาสตร์เลเซอร์ผิวหนัง ปฎิบัติงานวิจัยที่ Wellman Center for Photomedicine มหาวิทยาลัยฮาร์วาร์ด มลรัฐแมสซาซูเสตส์ สหรัฐอเมริกา ในปี 2011-2013 ภายใต้การดูแลของ Prof. Richard Rox Anderson แพทย์ผิวหนังและนักประดิษฐ์เครื่องเลเซอร์ผิวหนังที่มีชื่อเสียงระดับโลกจากทฤษฎี Selective Photothermolysis* ทีมวิจัยมีเป้าหมายที่จะพัฒนาเทคนิคใหม่ที่สามารถเปลี่ยนรูปร่างและปรับทิศทางเนื้อเยื่อตามที่กำหนดโดยใช้อุปกรณ์เลเซอร์
จากการประยุกต์เครื่องมือ Fractional Ablative Laser และเทคนิคในการปิดหลุมเล็กระดับจุลภาค ผลการทดลองในสัตว์ (in-vivo) และผิวหนังคน (ex-vivo) สนับสนุนสมมติฐานที่ทำให้ลดพื้นที่ผิวและเปลี่ยนทิศทางเนื้อเยื่อได้โดยไม่เกิดแผลเป็น การค้นพบนี้สามารถนำไปใช้ประโยชน์ด้านการแพทย์ในอนาคตในการรักษาความผิดปกติของผิวหนังได้หลายชนิด เช่น ลดความตึงผิวในผู้ป่วยไฟไหม้ การทำให้แผลปิด หรือการแก้ปัญหาความหย่อนคล้อย
แพทย์หญิงวิกันดาและคณะทีมวิจัยมหาวิทยาลัยฮาร์วาร์ด ได้ยื่นจดสิทธิบัตรของประเทศสหรัฐอเมริกา 6 รายการ 1,2,3,4,5,6
1. U.S. Patent No.11813218,(2023)
2. U.S. Patent publication No.20220054343,(2022)
3. U.S. Patent No.10888375,(2021)
4. U.S. Patent publication No.20180008500,(2018)
5. U.S. Patent publication No.20150173991,(2015)
6. U.S. Patent publication No.20150150629,(2015)
*การใช้แสงช่วงคลื่นที่เหมาะสมกับส่วนประกอบของผิวหนังที่เฉพาะเจาะจงสามารถให้ผลโดยตรงและทำลายเป้าหมายได้แม่นยำโดยไม่ทำลายองค์ประกอบข้างเคียง
Assist. Prof. Dr. Wikunda Limpiangkanan MD., certified Thai board of Dermatology who was granted research scholarship in field of laser surgery at Wellman Center for Photomedicine, Massachusette General Hospital, Harvard Medical School in 2011-2013. She was under supervision of Prof. Richard Rox Anderson, who is a pioneer in laser surgery and a world renowned dermatologist. Her group’s project was to develop a new technique to change the shape and predictably move soft tissue in a particular direction using lasers.
By modified fractional ablative treatment and followed by closure of microscopic holes, the results of in- vivo swine and ex-vivo human skin experiments supported the hypothesis that reducing skin area and moving skin in a preferred direction without causing scar was feasible. This application could be useful in treating some skin conditions such as relieving tension on burn scars, closing a wound or treating skin laxity in the near future.
Dr.Limpiangkanan has filed for patents by the United States Patent and Trademark Office (USPTO) to protect the following inventions.
1.METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
Publication number: 20220054343
Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater that about 0.2mm and less than about 0.7mm or 0.5mm, using a mechanical apparatus. Compressive and/or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and/or directional shrinkage of the treated skin area.
Type: Application
Filed: April 9, 2021
Publication date: February 24, 2022
Inventors: Richard R. Anderson, Mathew Avram, Fernanda H. Sakamoto, Wikunda Limpiangkanan, William A. Farinelli
2.METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
Patent number: 10888375
Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater that about 0.2mm and less than about 0.7mm or 0.5mm, using a mechanical apparatus. Compressive and/or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and/or directional shrinkage of the treated skin area.
Type: Grant
Filed: July 5, 2013
Date of Patent: January 12, 2021
Assignee: THE GENERAL HOSPITAL CORPORATION
Inventors: Richard R. Anderson, Mathew Avram, Wikunda Limpiangkanan, William A. Farinelli
3.METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
Publication number: 20180008500
Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater that about 0.2mm and less than about 0.7mm or 0.5mm, using a mechanical apparatus. Compressive and/or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and/or directional shrinkage of the treated skin area.
Type: Application
Filed: August 16, 2017
Publication date: January 11, 2018
Inventors: Richard R. Anderson, Mathew Avram, Fernanda H. Sakamoto, Wikunda Limpiangkanan, William A. Farinelli
4.METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
Publication number: 20150173991
Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater that about 0.2mm and less than about 0.7mm or 0.5mm, using a mechanical apparatus. Compressive and/or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and/or directional shrinkage of the treated skin area.
Type: Application
Filed: July 5, 2013
Publication date: June 25, 2015
Inventors: Richard R. Anderson, Mathew Avram, Fernanda H. Sakamoto, Wikunda Limpiangkanan, William A. Farinelli
5.METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
Publication number: 20150150629
Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater that about 0.2mm and less than about 0.7mm or 0.5mm, using a mechanical apparatus. Compressive and/or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and/or directional shrinkage of the treated skin area.
Type: Application
Filed: July 5, 2013
Publication date: June 4, 2015
Inventors: Richard R. Anderson, Mathew Avram, Wikunda Limpiangkanan, William A. Farinelli
6.METHOD AND APPARATUS FOR DERMATOLOGICAL TREATMENT
Publication number: 20150150629
Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g.,
having widths greater than about 0.2 mm and less than about 0.7 mm or 0.5 mm, using ablative electromagnetic radiation, e.g., optical energy.
An optically transparent plate or window can be pressed over a surface of the skin tissue as the holes are ablated to disrupt formation of a
thermal cuff around the holes. Compressive or tensile forces can then be applied to the treated region of the skin tissue as the damage heals
to facilitate hole closure and provide enhanced and/or directional shrinkage of the treated skin area.
Type: Application
Filed: July 5, 2013
Publication date: June 4, 2015
Inventors: Richard Rox Anderson, Mathew Avram, Wikunda Limpiangkanan, William A. Farinelli
